AOD-9604 5 mg

AOD-9604 for research: identity and specifications

AOD-9604 (CAS 221231-10-3) is a modified synthetic peptide fragment of human growth hormone (hGH), corresponding to the C-terminal region of the molecule with an additional tyrosine residue at the N-terminus. Supplied as a 5 mg vial, lyophilized powder, with no fillers, carriers or excipients, at ≥98% purity by HPLC, produced by solid-phase synthesis and purified by HPLC, with the lot-specific value reported on the certificate of analysis.

Scientific background

In preclinical literature, this fragment is studied in models of lipid metabolism, particularly lipolysis and lipogenesis in adipocytes and in rodents, as part of research into which regions of hGH account for each metabolic effect. Studies describe the absence, in these models, of the cell-growth and glucose-metabolism actions attributed to the intact molecule.

AOD-9604 is used in in vitro adipocyte assays and rodent models as a tool to separate the metabolic pathways of growth hormone from its growth pathways, always under controlled bench conditions and without extrapolating results to human or veterinary use.

• Lipolysis in cultured adipocytes and adipose tissue
• Comparative studies of lipid metabolism pathways in rodents
• Selectivity of growth hormone fragments versus the intact molecule
• Structure-activity relationship of the hGH C-terminal region

Technical specifications

Analytical quality and chain of custody

Every lot of AOD-9604 is synthesized in registered facilities, with independent analytical verification by third-party laboratories and full chain-of-custody documentation. The certificate of analysis (COA) for each lot can be reviewed before purchase, recording HPLC purity and the other quality-control parameters used to release the material.

Reconstitution and laboratory handling

As a bench procedure, the lyophilized vial is reconstituted with a known volume of a suitable solvent, added along the inner wall of the vial, followed by gentle swirling until fully dissolved, without vigorous shaking. The reconstituted solution should be kept refrigerated and protected from light, and used in controlled assays within the stability period validated by the laboratory. Handling must be performed only by qualified personnel, in a bench environment suitable for in vitro experimentation, with lot number and storage conditions documented according to good laboratory practice.

Frequently asked questions

What is the purity of the AOD-9604 supplied?

≥98% by HPLC, with the lot-specific value reported on the certificate of analysis (COA). The current lot, AOD05-032026-1, shows 99.233%.

Does AOD-9604 correspond to the intact growth hormone molecule?

No. It is a modified synthetic fragment, identified by PubChem CID 71300630 and formula C78H123N23O23S2, distinct from the full hGH molecule.

How should the compound be stored?

At -20 °C, protected from light and moisture, as a lyophilized powder until reconstitution.

Does the certificate of analysis come with the lot?

Yes, every lot has a matching COA that can be verified before purchase using the button on this page.

Who can purchase AOD-9604?

Sales are restricted to qualified researchers and institutions, for laboratory use only, as detailed in the research-use-only notice on this page.

See the peptide reference guide, the page on how every lot is tested by HPLC and COA and the molecular structure in the PubChem database.

Research use only (RUO). This material is supplied for in vitro laboratory research only. It is not a drug, dietary supplement or cosmetic, and it is not intended for human or veterinary use, or for the diagnosis or treatment of any condition. Sales are restricted to researchers and institutions.